The
Problem:
Retrosynthesis – working backwards from relatively complex
molecules to simpler ones.
Synthesis planning and retrosynthesis are the main
methods in use today for finding the cheapest, fastest
routes for making an organic compound. This method
starts at the completed molecule and works backward
until commercially available starting materials are
reached.
There are tens of thousands of known reactions, and at
least 1,000,000 possible starting compounds that could
be considered legitimate starting materials.
Theoretically there are millions of possible routes to
make any of the larger, more complex drugs such as Taxol.
However, no single individual or team of individuals can
possibly memorize or even chart all of the potential
possibilities in organic synthesis development and
retrosynthesis. The number of solutions they are capable
of finding to any given problem is severely limited.
The
synthesis planning system used to date has many inherent
shortcomings.
-
It is a very TIME consuming process
-
It is a very COSTLY process
-
It does not guarantee results
-
It does not guarantee that the results you do find, if any,
will be the most cost effective solution, or even
financially feasible
The
technologies needed to accomplish this task in a timely,
cost-effective manner that results in consistently
superior solutions to synthesize a particular compound
did not exist...
Until Now!
The Problem
The System
The Solution |